Laboratory animals as surrogate models of human obesity
نویسندگان
چکیده
منابع مشابه
Animals as Models or Analogs
Non-human animals are frequently the research subjects in a variety of areas, particularly in the life sciences. In 1997, the Canadian Council of Animal Care reported that 1 474 611 non-human animals were tested as part of research, testing, and teaching in Canada, a reduction from the 2 075 923 non-human animals that were tested in 1985. Most of these were tested as part of basic research in t...
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The use of animals as experimental organisms has been critical to the development of addiction research from the nineteenth century. They have been used as a means of generating reliable data regarding the processes of addiction that was not available from the study of human subjects. Their use, however, has been far from straightforward. Through focusing on the study of alcoholism, where the n...
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grows. Another line of attack on this problem is that of transplanting human tumours into laboratory animals. This provides a means of studying the effects of certain chemicals, hormones and viruses on human breast cancer outside the patient and gives a laboratory testing-ground for them before trial on patients. This paper describes briefly how human tumours can be grown in rats and hamsters f...
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Amphibians include over 4,500 species within 3 major lineages---caecilians, salamanders, and anurans (Stebbins and Cohen 1995). These lineages are linked by several unique physiological traits. The most prominent is the indirect lifestyle of many amphibians--the aquatic gillbreathing larval stage and the aquatic or terrestrial lung or skin-breathing adult stage. A second feature of amphibians i...
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ژورنال
عنوان ژورنال: Acta Pharmacologica Sinica
سال: 2012
ISSN: 1671-4083,1745-7254
DOI: 10.1038/aps.2011.203